The research topic focus on ultrasound imaging and biomedical signal processing, especially in the cross-field integration of medicine, physics and engineering. Research directions include high-resolution ultrasound imaging/ultrasonic contrast agent development, ultrasound contrast agent nonlinear imaging/drug delivery and control release, ultrasound molecular imaging and blood-brain barrier opening, ultrasound code-excitating imaging-aided diagnosis technology, ultrasound-induced thrombolysis technique development and ultrasonic liquid lens probe development.​