Patent name

Biomembrane Phase-Change Droplets (PCDs), Drug Carrier and Use Thereof

​專利名稱

生物膜相變液滴、藥物載體及其用途

Patent family

中華民國：I619514

Inventor

Chien-Wen Chang, Cheng-Chan Hsieh, Chih-Kuang Yeh, Yee Hsien Lin, Shih-Tsung Kang, Pei-Ying Chen

張建文,謝承展,葉秩光,林逸絃,康世聰,陳佩瑩

Abstract

The present invention provides biomembrane phase-change droplets (PCDs), including a hydrophobic liquid core; and a phospholipid-consisted biomembrane encapsulating the hydrophobic liquid core, wherein the hydrophobic liquid core being evaporated by an ultrasound irradiation. The present invention also provides a drug carrier, including a biomembrane phase-change droplets; and a hydrophobic drug embedded in the biomembrane of the biomembrane phase-change droplets, wherein the hydrophobic drug is present in an amount of 1~10 wt ％, based on the weight of the drug carrier. The present application further provides a use thereof.

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本發明提供一種生物膜相變液滴(droplet)，包括：一疏水性液體核心；以及具有磷脂質之一生物膜包覆疏水性液體核心；其中該疏水性液體核心經一超音波照射觸發汽化。本發明另提供一種藥物載體，包括：一生物膜相變液滴；以及一疏水性藥物，內嵌於上述之生物膜相變液滴之生物膜上；其中疏水性藥物佔藥物載體之重量百分比為1~10wt％。本發明亦提供上述生物膜相變液滴及藥物載體的用途。